Role of nicotinic acetylcholine receptors in regulating dopamine neuron activity

Highlights • Nicotinic modulation of dopaminergic neurons. • Do nicotinic receptor subtypes play a role in defining functional DAergic subpopulations? • Influences of nicotinic modulation at the cellular, systemic and behavioral levels. • Implications in the reinforcing effects of nicotine.

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Bibliographische Detailangaben
Veröffentlicht in:	Neuroscience 2014-12, Vol.282, p.86-100
Hauptverfasser:	Faure, P, Tolu, S, Valverde, S, Naudé, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Behavior, Animal - physiology dopamine Dopaminergic Neurons - metabolism Life Sciences nAChRs Neurology Neurons and Cognition nicotine Nicotine - metabolism Receptors, Nicotinic - physiology substantia nigra Substantia Nigra - metabolism Substantia Nigra - physiology Ventral Tegmental Area - metabolism Ventral Tegmental Area - physiology VTA
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Beschreibung
Zusammenfassung:	Highlights • Nicotinic modulation of dopaminergic neurons. • Do nicotinic receptor subtypes play a role in defining functional DAergic subpopulations? • Influences of nicotinic modulation at the cellular, systemic and behavioral levels. • Implications in the reinforcing effects of nicotine.
ISSN:	0306-4522 1873-7544
DOI:	10.1016/j.neuroscience.2014.05.040