Involvement of NO in gastric emptying of semi‐solid meal in conscious pigs

The influence of non‐selective nitric oxide synthase (NOS) inhibition on gastric emptying of a semi‐solid meal was studied in conscious pigs. Antro‐duodenal motility and fundic compliance were also assessed to evaluate the mechanisms at the origin of potential alteration in gastric emptying pattern....

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neurogastroenterology and motility 2005-04, Vol.17 (2), p.229-235
Hauptverfasser:	Lefebvre, R. A., Dick, J. M. C., Guérin, S., Malbert, C.‐H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Pressure - physiology Compliance Enzyme Inhibitors - pharmacology Female fundic compliance gastric emptying Gastric Emptying - physiology Life Sciences Muscle Contraction - physiology NG-Nitroarginine Methyl Ester - pharmacology Nitric Oxide - metabolism nitric oxide synthase Nitric Oxide Synthase - metabolism pig Stomach - physiology Swine
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The influence of non‐selective nitric oxide synthase (NOS) inhibition on gastric emptying of a semi‐solid meal was studied in conscious pigs. Antro‐duodenal motility and fundic compliance were also assessed to evaluate the mechanisms at the origin of potential alteration in gastric emptying pattern. NG‐nitro‐l‐arginine methyl ester (l‐NAME; 20 mg kg−1 i.v.) delayed gastric emptying (half‐emptying time of 128.98 ± 16.86 min vs 73.74 ± 7.73 min after saline, P
ISSN:	1350-1925 1365-2982
DOI:	10.1111/j.1365-2982.2004.00604.x