Endothelial precursor cell-based therapy to target the pathologic angiogenesis and compensate tumor hypoxia
Highlights • A model of tumor homing-cell based targeting of pathologic angiogenesis. • Defined endothelial precursor cells selectively seeking into the tumor vessels. • Potential cell therapy normalizing tumor angiogenesis by endothelial precursor cells. • Tumor microenvironment modification by fun...
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Veröffentlicht in: | Cancer letters 2016-01, Vol.370 (2), p.345-357 |
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Hauptverfasser: | , , , , , , , , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | Highlights • A model of tumor homing-cell based targeting of pathologic angiogenesis. • Defined endothelial precursor cells selectively seeking into the tumor vessels. • Potential cell therapy normalizing tumor angiogenesis by endothelial precursor cells. • Tumor microenvironment modification by functional angiogenesis/vasculogenesis. • Endothelial precursor cells as carriers of therapeutic agents to tumor. |
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ISSN: | 0304-3835 1872-7980 |
DOI: | 10.1016/j.canlet.2015.11.008 |