Salivary cortisol in early psychosis: New findings and meta-analysis

Highlights • No significant differences in basal salivary cortisol level between ultra-high risk subjects, first-episode of psychosis and help-seekers. • Meta-analyses show that only cortisol level in UHR was increased compared to controls. • Basal salivary cortisol may not be a valid biomarker for...

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Veröffentlicht in:	Psychoneuroendocrinology 2016-01, Vol.63, p.262-270
Hauptverfasser:	Chaumette, Boris, Kebir, Oussama, Mam-Lam-Fook, Célia, Morvan, Yannick, Bourgin, Julie, Godsil, Bill P, Plaze, Marion, Gaillard, Raphaël, Jay, Thérèse M, Krebs, Marie-Odile
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age of Onset Case-Control Studies Cognitive science Cohort Studies Early Diagnosis Endocrinology & Metabolism Female Humans Hydrocortisone - metabolism Hypothalamo-Hypophyseal System - metabolism Hypothalamo-Hypophyseal System - physiopathology Male Neuropsychological Tests Pituitary-Adrenal System - metabolism Pituitary-Adrenal System - physiopathology Psychiatry Psychology Psychotic Disorders - diagnosis Psychotic Disorders - epidemiology Psychotic Disorders - metabolism Psychotic Disorders - pathology Saliva - metabolism Young Adult
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Zusammenfassung:	Highlights • No significant differences in basal salivary cortisol level between ultra-high risk subjects, first-episode of psychosis and help-seekers. • Meta-analyses show that only cortisol level in UHR was increased compared to controls. • Basal salivary cortisol may not be a valid biomarker for clinical staging/psychotic transition prediction.
ISSN:	0306-4530 1873-3360
DOI:	10.1016/j.psyneuen.2015.10.007