Quality Control Initiative on the Evaluation of the Dysmegakaryopoiesis in Myeloid Neoplasms: Difficulties in the Assessment of Dysplasia

Highlights • The presence of micromegakaryocytes correlates strongly with myeloid neoplasia • Micromegakaryocytes can be identified reliably • Multinucleated megakaryocytes are not specific for myeloid neoplasia • Cytoplasmic dysplasia is not useful in recognising MDS • ‘Possibly dysplastic’ cells s...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Leukemia research 2016-06, Vol.45, p.75-81
Hauptverfasser:	Goasguen, Jean E, Bennett, John M, Bain, Barbara J, Brunning, Richard D, Vallespí, Maria-Teresa, Tomonaga, Masao, Zini, Gina, Renault, Alain
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Cell Shape Cell Size Dysmegakaryocytopoiesis Dysmegakaryopoiesis Dysmyelopoiesis Dysplastic features Hematologic Neoplasms - pathology Hematology Hematology, Oncology and Palliative Medicine Human health and pathology Humans Life Sciences Megakaryocyte Progenitor Cells Megakaryocytes Megakaryocytes - pathology Myelodysplastic syndrome Myelodysplastic Syndromes - diagnosis Myeloproliferative Disorders - diagnosis Quality Control Tissues and Organs
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights • The presence of micromegakaryocytes correlates strongly with myeloid neoplasia • Micromegakaryocytes can be identified reliably • Multinucleated megakaryocytes are not specific for myeloid neoplasia • Cytoplasmic dysplasia is not useful in recognising MDS • ‘Possibly dysplastic’ cells should be excluded from counts in suspected MDS
ISSN:	0145-2126 1873-5835 0145-2126
DOI:	10.1016/j.leukres.2016.04.009