Glucose and hypothalamic astrocytes: More than a fueling role?

Highlights • Main historical and recent data on astrocyte’s role in hypothalamic glucose sensing and disturbances in metabolic diseases. • Focus on the role of the astroglial network in hypothalamic glucose sensing, especially connexins 43 formed gap-junctions. • Update of presumed and hypothetical...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neuroscience 2016-05, Vol.323, p.110-120
Hauptverfasser:	Leloup, C, Allard, C, Carneiro, L, Fioramonti, X, Collins, S, Pénicaud, L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Astrocytes - metabolism astroglial gap junctions astroglial hemichannels connexins 30 and 43 Food and Nutrition Gap Junctions - metabolism glucose Glucose - metabolism Humans hypothalamic glucose sensing Hypothalamus - metabolism lactate Life Sciences Neurology Neurons and Cognition
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights • Main historical and recent data on astrocyte’s role in hypothalamic glucose sensing and disturbances in metabolic diseases. • Focus on the role of the astroglial network in hypothalamic glucose sensing, especially connexins 43 formed gap-junctions. • Update of presumed and hypothetical pathways in this mechanism.
ISSN:	0306-4522 1873-7544
DOI:	10.1016/j.neuroscience.2015.06.007