Towards a Robust and Reliable Method for the Reduction of Functionalized Sulfoxides

Towards a Robust and Reliable Method for the Reduction of Functionalized Sulfoxides

Several functionalized sulfoxides in the modafinil series, which bear another reducible function, were chemoselectively reduced to thioethers using the KI/AcCl system.

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Veröffentlicht in:Organic process research & development 2008-07, Vol.12 (4), p.614-617
Hauptverfasser: Ternois, James, Guillen, Frédéric, Piacenza, Guy, Rose, Sébastien, Plaquevent, Jean-Christophe, Coquerel, Gérard
Format: Artikel
Sprache:eng
Schlagworte:
Chemical Sciences
Organic chemistry
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Beschreibung
Zusammenfassung:Several functionalized sulfoxides in the modafinil series, which bear another reducible function, were chemoselectively reduced to thioethers using the KI/AcCl system.
ISSN:1083-6160
1520-586X
DOI:10.1021/op800088x