Docetaxel-induced photo-recall phenomenon

Photo‐recall phenomenon is a phototoxic eruption occurring on areas of previous ultraviolet‐induced solar erythema following a systemic administration of a drug. It has been mostly described with methotrexate but remains rare with other antineoplastic drugs. We describe a case of docetaxel‐induced p...

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Veröffentlicht in:Photodermatology, photoimmunology & photomedicine photoimmunology & photomedicine, 2012-08, Vol.28 (4), p.222-223
Hauptverfasser: Droitcourt, Catherine, Le Hô, Hélêne, Adamski, Henri, Le Gall, François, Dupuy, Alain
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Sprache:eng
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Zusammenfassung:Photo‐recall phenomenon is a phototoxic eruption occurring on areas of previous ultraviolet‐induced solar erythema following a systemic administration of a drug. It has been mostly described with methotrexate but remains rare with other antineoplastic drugs. We describe a case of docetaxel‐induced photo‐recall skin rash in a woman treated for a non‐small‐cell lung cancer. Although the patient has refused to receive a second infusion, chemotherapy can be carried on with photoprotection and the use of topical and/or systemic corticosteroids. In contrast, radiation recall is a well‐known reaction by oncologists, most of them may not be aware of a similar phenomenon called photo‐recall phenomenon. Recognizing this entity may avoid misdiagnosing a drug allergy and should avoid inappropriate decisions of drug discontinuation.
ISSN:0905-4383
1600-0781
DOI:10.1111/j.1600-0781.2012.00669.x