New Insights Into Ventricular Interactions During Cardiac Resynchronization

[...]the selection of CRT candidates on this sole criterion is not optimal, given the high rate of nonresponders, consistently approximating 30% in most of the studies. [...]criteria assessing mechanical dyssynchrony by echocardiography were initially thought to improve patients' selection, but failed to demonstrate their usefulness in large prospective clinical trials (5). [...]a systolic ventricular interaction exists between both chambers such that LV contraction increases RV contraction.