Formylation of amines through catalyst- and solvent-free transamidation reaction

Formylation of amines through catalyst- and solvent-free transamidation reaction

The transamidation between formamide and various amines proceeds under heating, without any catalyst nor solvent, providing thus green and neutral conditions for the formylation of primary and secondary amines. The resulting amide product can be directly transformed, in a one pot sequence, into mono...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Tetrahedron letters 2014-01, Vol.55 (2), p.362-364
Hauptverfasser: Lebleu, Thomas, Kotsuki, Hiyoshizo, Maddaluno, Jacques, Legros, Julien
Format: Artikel
Sprache:eng
Schlagworte:
Amide
Amides
Amines
Catalysts
Chemical Sciences
Green chemistry
Heating
High pressure
Monomethylation
Neat conditions
Organic chemistry
Solvents
Tetrahedrons
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The transamidation between formamide and various amines proceeds under heating, without any catalyst nor solvent, providing thus green and neutral conditions for the formylation of primary and secondary amines. The resulting amide product can be directly transformed, in a one pot sequence, into monomethylamine.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2013.11.029