A track length estimator method for dose calculations in low-energy X-ray irradiations: implementation, properties and performance

The track length estimator (TLE) method, an “on-the-fly” fluence tally in Monte Carlo (MC) simulations, recently implemented in GATE 6.2, is known as a powerful tool to accelerate dose calculations in the domain of low-energy X-ray irradiations using the kerma approximation. Overall efficiency gains of the TLE with respect to analogous MC were reported in the literature for regions of interest in various applications (photon beam radiation therapy, X-ray imaging). The behaviour of the TLE method in terms of statistical properties, dose deposition patterns, and computational efficiency compared to analogous MC simulations was investigated. The statistical properties of the dose deposition were first assessed. Derivations of the variance reduction factor of TLE versus analogous MC were carried out, starting from the expression of the dose estimate variance in the TLE and analogous MC schemes. Two test cases were chosen to benchmark the TLE performance in comparison with analogous MC: (i) a small animal irradiation under stereotactic synchrotron radiation therapy conditions and (ii) the irradiation of a human pelvis during a cone beam computed tomography acquisition. Dose distribution patterns and efficiency gain maps were analysed. The efficiency gain exhibits strong variations within a given irradiation case, depending on the geometrical (voxel size, ballistics) and physical (material and beam properties) parameters on the voxel scale. Typical values lie between 10 and 103, with lower levels in dense regions (bone) outside the irradiated channels (scattered dose only), and higher levels in soft tissues directly exposed to the beams. Die Track-Length-Estimator (TLE)-Methode ist ein rechnerisch sehr effizientes Verfahren für Monte-Carlo (MC)-Simulationen, welches kürzlich in GATE 6.2 implementiert wurde. Sie wird zur Beschleunigung der Dosisberechnungen im Umfeld der niederenergetischen Röntgenstrahlung mit Hilfe der Kerma-Annährung eingesetzt. Über die Effizienzsteigerung der TLE-Mehode im Vergleich mit der analogen MC-Methode wurde in der Literatur in Bezug auf zahlreiche Anwendungen (darunter Strahlentherapie, Röntgenbildgebung) berichtet. Wir haben die TLE-Methode hinsichtlich statistischer Größen, Strahlendosisverteilungen und Recheneffizienz im Vergleich mit analogen MC-Simulationen untersucht. Zunächst wurden die statistischen Eigenschaften der abgegebenen Röntgendosis analysiert. Ausgehend vom jeweiligen Ausdruck der mit der Dosisabschätzung verbunden