Foxl2 gene and the development of the ovary : a story about goat, mouse, fish and woman

In this review, we describe recent results concerning the genetics of sex determination in mammals. Particularly, we developed the study of the FOXL2 gene and its implication in genetic anomalies in goats (PIS mutation) and humans (BPES). We present the expression of FOXL2 in the ovaries of differen...

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Veröffentlicht in:	Reproduction, nutrition, development nutrition, development, 2005-05, Vol.45 (3), p.377-382
Hauptverfasser:	BARON, Daniel, BATISTA, Frank, PANNETIER, Maëlle, VAIMAN, Daniel, VIGIER, Bernard, VEITIA, Reiner, FELLOUS, Marc, CHAFFAUX, Stéphane, COCQUET, Julie, COTINOT, Corinne, CRIBIU, Edmond, DE BAEREE, Elfride, GUIGUEN, Yann, JAUBERT, Francis, PAILHOUX, Eric
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Development Biology Disorders of Sex Development DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Female Fishes Food and Nutrition Forkhead Box Protein L2 Forkhead Transcription Factors Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Developmental Goats Humans Life Sciences Male Mice Ovary - embryology Ovary - metabolism Reproductive Biology Sex Determination Processes Species Specificity Transcription Factors - genetics Transcription Factors - metabolism Transcription, Genetic Vertebrates: reproduction
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Zusammenfassung:	In this review, we describe recent results concerning the genetics of sex determination in mammals. Particularly, we developed the study of the FOXL2 gene and its implication in genetic anomalies in goats (PIS mutation) and humans (BPES). We present the expression of FOXL2 in the ovaries of different species.
ISSN:	0926-5287 1297-9708
DOI:	10.1051/rnd:2005028