Release and transportation of Hedgehog molecules

Highlights ► Lipidated Hedgehog proteins spread in the hydrophilic extracellular space. ► Different Hedgehog carriers are involved in short and long range transportation. ► Carriers for Hedgehog work in parallel in the same cells.

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Bibliographische Detailangaben
Veröffentlicht in:	Current opinion in cell biology 2012-04, Vol.24 (2), p.173-180
1. Verfasser:	Thérond, Pascal P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carrier Proteins Carrier Proteins - isolation & purification Cell Membrane Cell Membrane - metabolism Cholesterol Cholesterol - metabolism Development Biology Extracellular Space Extracellular Space - chemistry Extracellular Space - metabolism Hedgehog Proteins Hedgehog Proteins - metabolism Internal Medicine Life Sciences Morphogenesis Palmitic Acid Palmitic Acid - metabolism Protein Processing, Post-Translational Protein Transport
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Beschreibung
Zusammenfassung:	Highlights ► Lipidated Hedgehog proteins spread in the hydrophilic extracellular space. ► Different Hedgehog carriers are involved in short and long range transportation. ► Carriers for Hedgehog work in parallel in the same cells.
ISSN:	0955-0674 1879-0410
DOI:	10.1016/j.ceb.2012.02.001