Dual Heterogeneous Catalysis for a Regioselective Three- Component Synthesis of Bi- and Tri(hetero)arylpyridines

We have designed a new, user‐friendly oxidative dual heterogeneous catalytic system capable of promoting polysubstituted pyridines as unique products from simple activated Michael acceptors, 1,3‐dicarbonyls and ammonium acetate. This metal‐free environmentally‐respectful and totally regioselective domino reaction proved to be a great strategy to access bi‐ and triaryl‐type pyridines as well as challenging bi‐ and triheteroaryl‐type pyridines in a single operation.