Self-Assembling Peptide-Based Nanoparticles for siRNA Delivery in Primary Cell Lines

The secondary amphipathic peptide CADY forms stable positively charged nanoparticles with short interfering RNA (siRNA), which involves both electrostatic and hydrophobic interactions. CADY/siRNA self‐assembling nanoparticles adopt a “raspberry”‐like architecture cemented together by a matrix of fre...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Small (Weinheim an der Bergstrasse, Germany) Germany), 2012-07, Vol.8 (14), p.2184-2188
Hauptverfasser:	Deshayes, Sébastien, Konate, Karidia, Rydström, Anna, Crombez, Laurence, Godefroy, Cédric, Milhiet, Pierre-Emmanuel, Thomas, Annick, Brasseur, Robert, Aldrian, Gudrun, Heitz, Frédéric, Muñoz-Morris, Maria A., Devoisselle, Jean-Marie, Divita, Gilles
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry, Molecular Biology Cell Line Cell Membrane Permeability Cell-Penetrating Peptides - chemistry Drug Carriers - chemistry drug delivery Humans Jurkat Cells Life Sciences nanoparticles Nanoparticles - administration & dosage Nanoparticles - chemistry peptides Peptides - chemistry RNA, Small Interfering - administration & dosage RNA, Small Interfering - chemistry self-assembly siRNA
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!