A Zinc-Sensing Glucose-Based Naphthyl Imino Conjugate as a Detecting Agent for Inorganic and Organic Phosphates, Including DNA

A Zinc-Sensing Glucose-Based Naphthyl Imino Conjugate as a Detecting Agent for Inorganic and Organic Phosphates, Including DNA

Sugars' sense of zinc: A glucose‐based naphthylimino conjugate (L) has been synthesized and structurally characterized. L has been shown to exhibit selective turn‐on fluorescence towards Zn2+ in an aqueous alcoholic medium. The zinc complex, in turn, recognizes phosphates, nucleotides, and DNA...

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Veröffentlicht in:Chemistry : a European journal 2011-07, Vol.17 (29), p.8044-8047
Hauptverfasser: Mitra, Atanu, Hinge, Vijaya Kumar, Mittal, Ankit, Bhakta, Snehasis, Guionneau, Philippe, Rao, Chebrolu P.
Format: Artikel
Sprache:eng
Schlagworte:
Biosensing Techniques - methods
Chemical Sciences
Chemistry
Conjugates
Deoxyribonucleic acid
DNA - analysis
Fluorescence
Glucose - chemistry
glycoconjugates
Glycoconjugates - chemistry
Material chemistry
Molecular dynamics
Molecular Dynamics Simulation
Nucleotides
Organophosphates - analysis
Phosphates
Phosphates - analysis
Sensitivity and Specificity
sensors
Simulation
Spectrometry, Fluorescence
Zinc
Zinc - analysis
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Zusammenfassung:Sugars' sense of zinc: A glucose‐based naphthylimino conjugate (L) has been synthesized and structurally characterized. L has been shown to exhibit selective turn‐on fluorescence towards Zn2+ in an aqueous alcoholic medium. The zinc complex, in turn, recognizes phosphates, nucleotides, and DNA by turn‐off fluorescence, which has been further investigated by molecular dynamics simulations.
ISSN:0947-6539
1521-3765
DOI:10.1002/chem.201100734