Perthamides C and D, two new potent anti-inflammatory cyclopeptides from a Solomon Lithistid sponge Theonella swinhoei
Two new metabolites, perthamides C and D, have been isolated from the marine sponge Theonella swinhoei. Their structures were determined by interpretation of NMR and ESIMS data. All compounds exhibited in vivo potent anti-inflammatory activity. Biological activity and structural elucidation are repo...
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| Veröffentlicht in: | Tetrahedron 2009-12, Vol.65 (50), p.10424-10429 |
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| container_title | Tetrahedron |
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| creator | Festa, Carmen De Marino, Simona Sepe, Valentina Monti, Maria Chiara Luciano, Paolo D'Auria, Maria Valeria Débitus, Cecile Bucci, Mariarosaria Vellecco, Valentina Zampella, Angela |
| description | Two new metabolites, perthamides C and D, have been isolated from the marine sponge
Theonella swinhoei. Their structures were determined by interpretation of NMR and ESIMS data. All compounds exhibited in vivo potent anti-inflammatory activity. Biological activity and structural elucidation are reported.
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| doi_str_mv | 10.1016/j.tet.2009.10.026 |
| format | Article |
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Theonella swinhoei. Their structures were determined by interpretation of NMR and ESIMS data. All compounds exhibited in vivo potent anti-inflammatory activity. Biological activity and structural elucidation are reported.
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| ispartof | Tetrahedron, 2009-12, Vol.65 (50), p.10424-10429 |
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| source | Elsevier ScienceDirect Journals Complete |
| subjects | Biochemistry, Molecular Biology Biological and medical sciences Bones, joints and connective tissue. Antiinflammatory agents Chemistry Exact sciences and technology General pharmacology Life Sciences Marine Medical sciences Organic chemistry Peptides Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Preparations and properties Theonella swinhoei |
| title | Perthamides C and D, two new potent anti-inflammatory cyclopeptides from a Solomon Lithistid sponge Theonella swinhoei |
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