Cell Migration: MIM Takes the Driver's Seat

Cell Migration: MIM Takes the Driver's Seat

A recent study reports a novel and conserved function for the I-BAR protein MIM in guiding cell migration: MIM has an anti-endocytic activity that moderates intracellular signalling of guidance cues by sequestration of cortactin.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Current biology 2010-07, Vol.20 (14), p.R606-R608
Hauptverfasser: Van De Bor, Véronique, Noselli, Stéphane
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Cell Movement - physiology
Cortactin - metabolism
Development Biology
Drosophila - embryology
Drosophila - physiology
Drosophila Proteins - metabolism
Life Sciences
Microfilament Proteins - metabolism
Models, Biological
Signal Transduction - physiology
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A recent study reports a novel and conserved function for the I-BAR protein MIM in guiding cell migration: MIM has an anti-endocytic activity that moderates intracellular signalling of guidance cues by sequestration of cortactin.
ISSN:0960-9822
1879-0445
DOI:10.1016/j.cub.2010.05.045