Dynamic Imaging of Functionalized Multi-Walled Carbon Nanotube Systemic Circulation and Urinary Excretion

Intravenously administered multi‐walled carbon nanotubes, functionalized with DTPA and radiolabeled with Indium‐111, were dynamically tracked in vivo using a microSingle Photon Emission Tomography scanner. Imaging showed that nanotubes enter the systemic blood circulation and within 5 min begin to p...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Advanced materials (Weinheim) 2008-01, Vol.20 (2), p.225-230
Hauptverfasser:	Lacerda, L., Soundararajan, A., Singh, R., Pastorin, G., Al-Jamal, K. T., Turton, J., Frederik, P., Herrero, M. A., Li, S., Bao, A., Emfietzoglou, D., Mather, S., Phillips, W. T., Prato, M., Bianco, A., Goins, B., Kostarelos, K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical applications Carbon nanotubes Carbon nanotubes, multiwalled Chemical Sciences Medicinal Chemistry multiwalled Nanomaterials
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Intravenously administered multi‐walled carbon nanotubes, functionalized with DTPA and radiolabeled with Indium‐111, were dynamically tracked in vivo using a microSingle Photon Emission Tomography scanner. Imaging showed that nanotubes enter the systemic blood circulation and within 5 min begin to permeate through the renal glomerular filtration system into the bladder.
ISSN:	0935-9648 1521-4095
DOI:	10.1002/adma.200702334