Studies on the stability of the cyclobutane b-aminoacid skeleton : a cautionary tale
The 2-amino-1-cyclobutanecarboxylic acid skeleton undergoes facile retro-Mannich type ring opening in solution, which may lead to unexpected by-products during its synthesis or manipulation
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| Veröffentlicht in: | Tetrahedron letters 2004, Vol.45, p.2359-2361 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
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| Online-Zugang: | Volltext |
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| Zusammenfassung: | The 2-amino-1-cyclobutanecarboxylic acid skeleton undergoes facile retro-Mannich type ring opening in solution, which may lead to unexpected by-products during its synthesis or manipulation |
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| ISSN: | 0040-4039 1873-3581 |
| DOI: | 10.1016/j.tet.2004.01.084 |