Efficient Diastereoselective Intermolecular Rhodium-Catalyzed CH Amination

Efficient Diastereoselective Intermolecular Rhodium-Catalyzed CH Amination

Successful matchmaking: The combination of a chiral nitrene precursor with a chiral rhodium(II) catalyst is the key factor that allows efficient intermolecular regioselective CH amination. Good‐to‐excellent yields and excellent diastereoselectivities can be obtained with a stoichiometric amount of...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Angewandte Chemie International Edition 2006-07, Vol.45 (28), p.4641-4644
Hauptverfasser: Liang, Chungen, Robert-Peillard, Fabien, Fruit, Corinne, Müller, Paul, Dodd, Robert H., Dauban, Philippe
Format: Artikel
Sprache:eng
Schlagworte:
amination
Chemical Sciences
CH insertion
hypervalent iodine
nitrenes
Organic chemistry
rhodium
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Successful matchmaking: The combination of a chiral nitrene precursor with a chiral rhodium(II) catalyst is the key factor that allows efficient intermolecular regioselective CH amination. Good‐to‐excellent yields and excellent diastereoselectivities can be obtained with a stoichiometric amount of the CH bond containing substrate. nttl=N‐1,8‐naphthoyl‐tert‐leucine.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200601248