Constituents of Burasaïa madagascarensis: A New Clerodane-Type Diterpene

Abstract From an ethanol extract of the stems of BURASAïA MADAGASCARENSIS Thouars (Menispermaceae) were isolated N-acetylnornuciferine and two clerodane-type diterpenes, one of them, epicordatine, being new. The structures were established by the interpretation of the spectral data. All the describe...

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Veröffentlicht in:	Planta medica 2002-04, Vol.68 (4), p.377-379
Hauptverfasser:	Mambu, Lengo, Ramanandraibe, Voahangy, Martin, Marie Thérèse, Blond, Alain, Grellier, Philippe, Frappier, François
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antiparasitic agents Biochemistry Biochemistry, Molecular Biology Biological and medical sciences Diterpenes - chemistry Diterpenes - isolation & purification Diterpenes - pharmacology Diterpenes, Clerodane Furans - chemistry Furans - isolation & purification Furans - pharmacology General pharmacology Humans Hypoxanthine - pharmacokinetics Letter Life Sciences Magnetic Resonance Spectroscopy Medical sciences Molecular Structure Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Extracts - chemistry Plant Extracts - isolation & purification Plant Extracts - pharmacology Plant Stems - chemistry Plasmodium falciparum - drug effects Plasmodium falciparum - metabolism Tritium
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Zusammenfassung:	Abstract From an ethanol extract of the stems of BURASAïA MADAGASCARENSIS Thouars (Menispermaceae) were isolated N-acetylnornuciferine and two clerodane-type diterpenes, one of them, epicordatine, being new. The structures were established by the interpretation of the spectral data. All the described compounds exhibited weak antimalarial activity.
ISSN:	0032-0943 1439-0221
DOI:	10.1055/s-2002-26748