Biokinetics and assessment of intake of thorium dioxide

The aim of this work was to investigate the biokinetics of thorium dioxide in animals for the purpose of assessing intakes of the compound by workers and the resulting doses. The results imply that measurements of the decay products in the chest or extrapolations from urine analysis data are unlikel...

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Veröffentlicht in:	Radiation protection dosimetry 2003-01, Vol.105 (1-4), p.115-118
Hauptverfasser:	A. Hodgson, S., N. Stradling, G., Hodgson, A., J. Smith, T., J. Youngman, M., Ansoborlo, E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption Administration, Inhalation Air Pollutants, Radioactive - analysis Animals Biological and medical sciences Bronchoalveolar Lavage Computer Science Computer Simulation Female Humans Inhalation Exposure - analysis Injections, Intravenous Lung - metabolism Medical sciences Metabolic Clearance Rate Models, Biological Nuclear Experiment Numerical Analysis Occupational Exposure - analysis Physics Radiation Dosage Radiometry - methods Rats Respiratory System - metabolism Thorax - metabolism Thorium Dioxide - administration & dosage Thorium Dioxide - analysis Thorium Dioxide - pharmacokinetics Urinalysis
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Beschreibung
Zusammenfassung:	The aim of this work was to investigate the biokinetics of thorium dioxide in animals for the purpose of assessing intakes of the compound by workers and the resulting doses. The results imply that measurements of the decay products in the chest or extrapolations from urine analysis data are unlikely to be of value for doses below 20 mSv. Even higher doses should be interpreted with caution as a consequence of uncertainties in particle size distribution and variations in dietary excretion.
ISSN:	0144-8420 1742-3406
DOI:	10.1093/oxfordjournals.rpd.a006204