Patterns of transmitted HIV drug resistance in Europe vary by risk group

Patterns of transmitted HIV drug resistance in Europe vary by risk group

Background: In Europe, a continuous programme (SPREAD) has been in place for ten years to study transmission of drug resistant HIV. We analysed time trends of transmitted drug resistance mutations (TDRM) in relation to the risk behaviour reported. Methods: HIV-1 patients newly diagnosed in 27 countr...

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Hauptverfasser: Frentz, Dineke, van de Vijver, David, Abecasis, Ana, Albert, Jan, Hamouda, Osamah, Jørgensen, Louise, Kücherer, Claudia, Struck, Daniel, Schmit, Jean-Claude, Vercauteren, Jurgen, Åsjö, Birgitta, Balotta, Claudia, Bergin, Colm, Beshkov, Danail, Camacho, Ricardo, Clotet, Bonaventura, Griskevicius, Algirdas, Grossman, Zehava, Horban, Andrzej, Kolupajeva, Tatjana, Korn, Klaus, Kostrikis, Leondios, Linka, Kirsi Liitsola Marek, Nielsen, Claus, Otelea, Dan, Paraskevis, Dimitrios, Paredes, Roger, Poljak, Mario, Puchhammer-Stöckl, Elisabeth, Sönnerborg, Anders, Stanekova, Danica, Stanojevic, Maja, Vandamme, Anne-Mieke, Boucher, Charles, Wensing, Annemarie, SPREAD Programme, on behalf of the, Vandekerckhove, Linos
Format: Artikel
Sprache:eng
Schlagworte:
ACTIVE ANTIRETROVIRAL THERAPY
APPEARANCE
EPIDEMIOLOGY
INDIVIDUALS
INFECTION
Medicine and Health Sciences
MUTATIONS
POPULATIONS
PREVALENCE
TRANSMISSION
USERS
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Zusammenfassung:Background: In Europe, a continuous programme (SPREAD) has been in place for ten years to study transmission of drug resistant HIV. We analysed time trends of transmitted drug resistance mutations (TDRM) in relation to the risk behaviour reported. Methods: HIV-1 patients newly diagnosed in 27 countries from 2002 through 2007 were included. Inclusion was representative for risk group and geographical distribution in the participating countries in Europe. Trends over time were calculated by logistic regression. Results: From the 4317 patients included, the majority was men-having-sex-with-men -MSM (2084, 48%), followed by heterosexuals (1501, 35%) and injection drug users (IDU) (355, 8%). MSM were more often from Western Europe origin, infected with subtype B virus, and recently infected (
ISSN:1932-6203
1932-6203