Relationship between genome and epigenome : challenges and requirements for future research

Relationship between genome and epigenome : challenges and requirements for future research

Understanding the links between genetic, epigenetic and non-genetic factors throughout the lifespan and across generations and their role in disease susceptibility and disease progression offer entirely new avenues and solutions to major problems in our society. To overcome the numerous challenges,...

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Hauptverfasser: Almouzni, Geneviève, Altucci, Lucia, Amati, Bruno, Ashley, Neil, Baulcombe, David, Beaujean, Nathalie, Bock, Christoph, Bongcam-Rudloff, Erik, Bousquet, Jean, Braun, Sigurd, Bressac-de Paillerets, Brigitte, Bussemakers, Marion, Clarke, Laura, Conesa, Ana, Estivill, Xavier, Fazeli, Alireza, Grgurević, Neža, Gut, Ivo, Heijmans, Bastiaan T, Hermouet, Sylvie, Houwing-Duistermaat, Jeanine, Iacobucci, Ilaria, Ilaš, Janez, Kandimalla, Raju, Krauss-Etschmann, Susanne, Lasko, Paul, Lehmann, Sören, Lindroth, Anders, Majdić, Gregor, Marcotte, Eric, Martinelli, Giovanni, Martinet, Nadine, Meyer, Eric, Miceli, Cristina, Mills, Ken, Moreno-Villanueva, Maria, Morvan, Ghislaine, Nickel, Dörthe, Niesler, Beate, Nowacki, Mariusz, Nowak, Jacek, Ossowski, Stephan, Pelizzola, Mattia, Pochet, Roland, Potočnik, Uroš, Radwanska, Magdalena, Raes, Jeroen, Rattray, Magnus, Robinson, Mark D, Roelen, Bernard, Sauer, Sascha, Schinzer, Dieter, Slagboom, Eline, Spector, Tim, Stunnenberg, Hendrik G, Tiligada, Ekaterini, Torres-Padilla, Maria-Elena, Tsonaka, Roula, Van Soom, Ann, Vidakovič, Melita, Widschwendter, Martin
Format: Artikel
Sprache:eng
Schlagworte:
CANCER
DEATH
DNA METHYLATION
INHIBITION
STEM-CELLS
Veterinary Sciences
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Zusammenfassung:Understanding the links between genetic, epigenetic and non-genetic factors throughout the lifespan and across generations and their role in disease susceptibility and disease progression offer entirely new avenues and solutions to major problems in our society. To overcome the numerous challenges, we have come up with nine major conclusions to set the vision for future policies and research agendas at the European level.
ISSN:1471-2164
1471-2164