Correlation of il-6 with D-dimer, LDH, S-ferritin biomarkers, comorbidities and clinical outcomes of COVID-19 patients admitted in a tertiary hospital in Coimbatore, India - a retrospective study based on 2,569 patients

Introduction: COVID-19 disease is associated with an excessive host immune response leading to multiorgan failures and immune- related manifestations. Clinical outcomes are influenced by disease severity, age, immune response, and comorbidity factors. In this retrospective study, we evaluated the correlation of Interleukin-6 (IL-6) with D-dimer, lactate dehydrogenase (LDH), Serum-ferritin, disease severity, and comorbidities of (nequivalent2569) COVID-19 patients. A retrospective analysis of data from COVID-19 patients has been evaluated and the correlation of IL-6 to biomarkers towards comorbidity factors, D-dimer, LDH, and S-Ferritin parameters was estimated. Materials and methods: Data from 2,569 COVID-19 patients 1687 males and 882 females were analysed. Results: Respiratory distress was higher in COVID-19 patients with IL-6 > 7pg/mL values (26.0% (453/1743) compared to patients with IL-6