EFFECTIVENESS OF BREADFRUIT LEAF EXTRACT COMPONENTS IN DIABETES MELLITUS PATIENTS IN BONE REGENCY - INDONESIA

Metabolic Syndrome (MetS) is a significant public health issue in Indonesia. While previous studies have found the effectiveness of breadfruit leaf capsules in improving metabolic status among prediabetics, limited studies exist on their effectiveness in people with Diabetes Mellitus (DM). This study aimed to assess the effectiveness of breadfruit leaves extract in improving components of MetS in patients with Diabetes Mellitus. The study was conducted as a double blind Randomized Controlled Trial (RCT). A total of 46 participants were recruited through public announcements. The intervention group received breadfruit leaf capsules, while the control group received placebo. Measurements of blood glucose, high density lipoprotein (HDL), triglycerides, blood pressure, consumption patterns, and anthropometry were conducted both before the intervention (pre-treatment) and after the 21-day intervention period (post-treatment). Data analysis was performed using SPSS software, employing independent t-tests and paired t-tests. Statistical significance was defined as a p-value