Biological and therapeutic effects of Cibotium barometz, traditional medicinal plant: A scoping review/Efectos biologicos y terapeuticos de Cibotium barometz, planta de la medicina tradicional: Revision exploratoria

This review aims to provide a current overview of the evidence for the biological and therapeutic effects of Cibotium barometz and its potential to treat various conditions. The present review was performed following the PRISMA-ScR guidelines. The search used PubMed, Scopus, Web of Science, Embase databases, and Google Scholar. The information extracted from the studies was synthesized qualitatively. Through the search, 902 records were found, of which, after the selection process, 17 full-text articles were evaluated, but only 14 articles met the eligibility criteria and were included in this review. The reported biological and therapeutic activities of Cibotium barometz are antioxidant, antimicrobial, antiviral, anticancer pretreatment, stimulation of chondrocyte proliferation, osteoprotective, and hepatoprotective. The evidence found suggests that C. barometz has various biological and therapeutic effects both in vitro and in vivo, which is why it is a relevant topic that could be considered to establish a more significant number of phytochemical characterization studies, as well as clinical studies that provide solid evidence and determine other possible therapeutic uses. Keywords: cibota; Gou-ji; Penghawar Djambi; woolly fern; complementary medicine. El proposito de esta revision es brindar un panorama actual de la evidencia de los efectos biologicos y terapeuticos de Cibotium barometz y su potencial para tratar diversas afecciones. La presente revision se realizo siguiendo las directrices de PRISMA-ScR. La busqueda se llevo a cabo en las bases de datos PubMed, Scopus, Web of Science y Embase asi como en Google Academico. La informacion extraida de los estudios se sintetizo de forma cualitativa. A traves de la busqueda se encontraron un total de 902 registros, de los cuales, despues del proceso de seleccion se evaluaron 17 articulos en texto completo, pero solo 14 articulos cumplieron los criterios de elegibilidad y fueron incluidos en esta revision. Las actividades biologicas y terapeuticas de Cibotium barometz reportadas son como antioxidante, antimicrobiano, antiviral, pretratamiento anticancerigeno, estimulacion de la proliferacion de condrocitos, osteoprotector y hepatoprotector. La evidencia encontrada sugiere que C. barometz posee diversos efectos biologicos y terapeuticos tanto in vitro como in vivo, motivo por el cual resulta un topico relevante que podria considerarse para establecer una mayor cantidad de estudios de caracterizacion fitoquim