LXR signaling pathways link cholesterol metabolism with risk for prediabetes and diabetes

FUNDING. The MESA Epigenomics and Transcriptomics Studies were funded by NIH grants 1R01HL101250, 1RF1AG054474, R01HL126477, R01DK101921, and R01HL135009. This work was supported by funding from NIDDK R01DK103531 and NHLBI R01HL119962.

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Bibliographische Detailangaben
Veröffentlicht in:	The Journal of clinical investigation 2024-05, Vol.134 (10)
Hauptverfasser:	Ding, Jingzhong, Nguyen, Anh Tram, Lohman, Kurt, Hensley, Michael T, Parker, Daniel, Hou, Li, Taylor, Jackson, Voora, Deepak, Sawyer, Janet K, Boudyguina, Elena, Bancks, Michael P, Bertoni, Alain, Pankow, James S, Rotter, Jerome I, Goodarzi, Mark O, Tracy, Russell P, Murdoch, David M, Rich, Stephen S, Psaty, Bruce M, Siscovick, David, Newgard, Christopher, Herrington, David, Hoeschele, Ina, Shea, Steven, Stein, James H, Patel, Manesh, Jacobs, Wendy Pos David, Jr, Parks, John S, Liu, Yongmei
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Atherosclerosis Cellular signal transduction Cholesterol Cholesterol metabolism Development and progression Genes Health aspects Insulin Insulin resistance Mediation Prediabetic state Risk factors RNA Type 2 diabetes
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Beschreibung
Zusammenfassung:	FUNDING. The MESA Epigenomics and Transcriptomics Studies were funded by NIH grants 1R01HL101250, 1RF1AG054474, R01HL126477, R01DK101921, and R01HL135009. This work was supported by funding from NIDDK R01DK103531 and NHLBI R01HL119962.
ISSN:	0021-9738
DOI:	10.1172/JCI173278.