Heat-Killed IL. helveticus/I Enhances Positive Mood States: A Randomized, Double-Blind, Placebo-Controlled Study

When mood states are impaired, daily life is severely disrupted. To maintain a specific mood state, both positive and negative moods must be controlled; however, methods to maintain a positive mood have not been fully established. Previous studies have suggested that heat-killed L. helveticus MCC184...

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Veröffentlicht in:Brain sciences 2023-06, Vol.13 (6)
Hauptverfasser: Mutoh, Natsumi, Kakiuchi, Izumi, Kato, Kumiko, Xu, Chendong, Iwabuchi, Noriyuki, Ayukawa, Masayo, Kiyosawa, Kyoko, Igarashi, Kazumi, Tanaka, Miyuki, Nakamura, Masahiko, Miyasaka, Mitsunaga
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Sprache:eng
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Zusammenfassung:When mood states are impaired, daily life is severely disrupted. To maintain a specific mood state, both positive and negative moods must be controlled; however, methods to maintain a positive mood have not been fully established. Previous studies have suggested that heat-killed L. helveticus MCC1848 has the potential to improve positive moods. This study aimed to test the efficacy of heat-killed L. helveticus MCC1848 in maintaining and improving a positive mood with PANAS, a questionnaire specifically designed to assess positive and negative mood, as the primary endpoint. Healthy Japanese nursing students (n = 46) were randomized to receive heat-killed L. helveticus MCC1848 (5 billion/day) or placebo powder for four weeks. Mood state was assessed before and two and four weeks after the intervention began; ingestion of heat-killed L. helveticus MCC1848 significantly improved PANAS 'Positive Affect' compared to the placebo. These results indicate that heat-killed L. helveticus MCC1848 is effective in enhancing positive mood.
ISSN:2076-3425
2076-3425
DOI:10.3390/brainsci13060973