Transcranial direct current stimulation study

The main goal of this paper is to present a biomarker using Event Related Potentials (ERPs) to assess the impact of Transcranial Direct Current Stimulation (tDCS) on brain activity during an attentional task. 13 participants (6 males, mean age 24.53 ± 4.5), participated in this study. tDCS was used to stimulate Dorso Lateral Prefrontal Cortex (DLPFC) for 5 consecutive days. Immediately before and after the tDCS sessions, the participants performed an Integrated Visual and Auditory-Adult Edition (IVA-AE) task while behavioral and neurophysiological responses were measured. As a result, tDCS led to a significant improvement in reaction time and an increase in visual P600 amplitude (p < 0.05). Also, the percent changes of P600 amplitude during visual target stimulation was significantly correlated with the percent changes of reaction time to visual targets (p = 0.007, r = -0.704). Consequently, tDCS applied over the DLPFC modulates executive function especially in visual attention during the IVA-AE task.