Increased D-dimers in Cerebral Sinovenous Thrombosis with Cardiac Myxoma

Numerous causes have been provided for the development of Cerebral Sinovenous Thrombosis (CSVT), which can be broadly divided into two categories-infectious, and non-infectious. Formation of thrombi in venous channels draining the brain is a consequence of the characteristic risk factors under the heading of Virchow's triad, which includes local trauma to vessel wall, stasis and a hypercoagulable state, the latter being the most important factor in development of CSVT. The diagnosis of CSVT is based on the presence of risk factors for venous thrombosis, to exclude a diagnosis using D-dimer, and brain imaging using MRI / MRV as gold standard. Myxoma in the heart causes the triad complications, which are the blockage associated with the size and location of the tumor, stasis, pulmonary and systemic embolism as well as the constitutional symptoms due to the release of pro-inflammatory cytokines due to hypercoagulability.