To Estimate Serum Calcium, Serum Phosphorus And 25 Vitamin D2 Levels In Sedentary And Less Exposed To Sun And Heavy Working Females Exposed To Sun

INTRODUCTION: Vitamin D is a steroid hormone involved in mineral ion homeostasis, it promotes calcium absorption in the gut and maintains adequate calcium and phosphate concentration for bone mineralization by osteoblasts and osteoclasts. Vitamin D levels are influenced by many factors such as; diet, geographical locations, physical activity and exposure to sunlight. With this background in mind the present study has been aimed to compare the values of 25(OH) vitamin D2, serum calcium and phosphorus levels in sedentary less exposed to sun and heavy working females exposed to sun. MATERIALS AND METHODS: The study is being conducted in the Department of Biochemistry, Subharti Medical College, Meerut. 100 apparently Healthy females of age group 21-50 years are included in the present study, out of which 50 are sedentary workers not exposed to sun(Case) and the rest 50 are labour class working 6-8 hours daily exposed to the sun (Control). 5ml of Venous Blood is taken in plain vials under all aseptic conditions from all individuals participated in the study. The samples are processed by technical laboratory methods and in related automatic machines (Vidas and Vitros 250). RESULT: The mean value of serum vitamin D (20.68 5.34), calcium (8.51 0.65) and phosphorous (4.03 0.33) in control groups are higher than the mean value of vitamin D (7.56 1.83) calcium (6.17 0.90) and phosphorous (3.36 0.48) in the case group and the mean difference between two groups is statistically significant (p 0.001) CONCLUSION: From this study it can be concluded that along with sun exposure one should take balanced diet, vitamin supplements and regular physical exercise to maintain adequate bone mineralization. The study is still in progress.