Iron Homeostasis and Its Related Biochemical Complications In Preeclampsia

Iron Homeostasis and Its Related Biochemical Complications In Preeclampsia

OBJECTIVE: To compare indices of iron homeostasis, low grade inflammation, oxidative stress and endothelial dysfunction between healthy pregnant women(HC) and Preeclampsia patients(PE). MATERIALS & METHODS: In a cross-sectional study Preeclampsia patients (n = 40) and healthy pregnant women (n =...

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Veröffentlicht in:Indian journal of clinical biochemistry 2022-05, Vol.32 (S1), p.S127
Hauptverfasser: Nila, S.G, Bobby, Zachariah, Jacob, Sajini Elizabeth, Dorairajan, Gowri
Format: Artikel
Sprache:eng
Schlagworte:
Analysis
Blood proteins
Complications and side effects
Ferritin
Homeostasis
Medical research
Medicine, Experimental
Preeclampsia
Pregnant women
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Zusammenfassung:OBJECTIVE: To compare indices of iron homeostasis, low grade inflammation, oxidative stress and endothelial dysfunction between healthy pregnant women(HC) and Preeclampsia patients(PE). MATERIALS & METHODS: In a cross-sectional study Preeclampsia patients (n = 40) and healthy pregnant women (n = 40) between 30 to 38 weeks of gestation both on Iron supplementation were recruited from OG department of JIPMER, Puducherry. Blood samples were collected from them and serum was stored for further analysis. Serum levels of Hepcidin, Transferrin, Ferritin, Iron, Hscrp, ADMA were measured by Elisa and MDA, TAS by Manual Methods. RESULTS : The serum levels of Iron (PE:703 [+ or -] 484 HC:393 [+ or -] 180 in [micro]g/dl; p
ISSN:0970-1915