Biomarkers in Early Diagnosis of Carcinoma Breast

Breast cancer is the third most common cancer in women accounting for highest morbidity and mortality worldwide. The increasing global burden emphasizes the need to understand the sequence of biochemical events taking place in tumor cells and to establish the role of certain biomarkers in early diagnosis. Tumor cells are known to produce Reactive Oxygen Species (ROS) at a greater pace than the non transformed cells, causing oxidative stress leading to cell proliferation, increased inflammatory conditions and progression of the disease.