Morphological Investigation of Protective Effects of CDP-Choline on Liver and Small Intestine in an Experimental Sepsis Model in Rats/Investigación Morfológica de los Efectos Protectores de la CDP-Colina en el Hígado y el Intestino Delgado en un Modelo Experimental de Sepsis en Ratas

Fifty male Wistar albino rats were divided into 5 groups; Group 1 as a sham group. Group 2 as a control group, Group 3 as 100 mg/kg CDP-choline administered group, Group as 200 mg/kg CDP-choline administered group, and Group 5 as sepsis group. The sepsis model was performed by ligating and perforating the caecum of rats. Liver and small intestine tissues were assessed either histologically or quantitatively and qualitatively. There was a significant difference between the sepsis and CDP-choline groups for liver and intestinal damage evaluated in tissue samples. (p