Synthesis and Antibacterial Activity of 5-Aryl-4-[hydroxyethyl]pyrrolidine-2,3-diones

The reaction of tryptamine with aromatic aldehydes and 4-chlorobenzoylpyruvic acid methyl ester led to the formation of 5-aryl-4-[hydroxy-(4-chlorophenyl)methylene]-1-[2-(1H-indol-3-yl)ethyl]pyrrolidine-2,3-diones. The resulting compounds were tested for antimicrobial activity.

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Bibliographische Detailangaben
Veröffentlicht in:	Russian journal of general chemistry 2020-08, Vol.90 (8), p.1426
Hauptverfasser:	Gein, V. L, Kazantseva, M. I, Varkentin, L. I, Zamaraeva, T. M, Yankin, A. N, Beletskii, E. V, Novikova, V. V
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-arrhythmia drugs Antibacterial agents
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	The reaction of tryptamine with aromatic aldehydes and 4-chlorobenzoylpyruvic acid methyl ester led to the formation of 5-aryl-4-[hydroxy-(4-chlorophenyl)methylene]-1-[2-(1H-indol-3-yl)ethyl]pyrrolidine-2,3-diones. The resulting compounds were tested for antimicrobial activity.
ISSN:	1070-3632
DOI:	10.1134/S1070363220080083