Effect of Mineralocorticoid Receptor Antagonists on the Prognosis of Patients with Ventricular Tachyarrhythmias

Introduction: The study sought to assess the effect of treatment with mineralocorticoid receptor antagonists (MRAs) on long-term prognosis of patients with systolic heart failure (HF) surviving index episodes of ventricular tachyarrhythmias. Methods: A large retrospective registry was used including...

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Veröffentlicht in:	Pharmacology 2022-01, Vol.107 (1-2), p.35-45
Hauptverfasser:	Schupp, Tobias, von Zworowsky, Max, Reiser, Linda, Abumayyaleh, Mohammad, Weidner, Kathrin, Mashayekhi, Kambis, Bertsch, Thomas, Abba, Mohammed L., Akin, Ibrahim, Behnes, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Cardiac patients Case-Control Studies Eplerenone - pharmacology Eplerenone - therapeutic use Female Germany Health aspects Heart Humans Male Middle Aged Mineralocorticoid Receptor Antagonists - pharmacology Mineralocorticoid Receptor Antagonists - therapeutic use Mortality Multivariate Analysis Prognosis Rankings Registries Research Article Retrospective Studies Spironolactone Spironolactone - pharmacology Spironolactone - therapeutic use Tachycardia Tachycardia, Ventricular - diagnosis Tachycardia, Ventricular - drug therapy Tachycardia, Ventricular - mortality Young Adult
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Zusammenfassung:	Introduction: The study sought to assess the effect of treatment with mineralocorticoid receptor antagonists (MRAs) on long-term prognosis of patients with systolic heart failure (HF) surviving index episodes of ventricular tachyarrhythmias. Methods: A large retrospective registry was used including consecutive HF patients with left ventricular ejection fraction
ISSN:	0031-7012 1423-0313
DOI:	10.1159/000520310