N-TERMINAL PROHORMONE OF BRAIN NATRIURETIC PEPTIDE IN THE DIAGNOSIS AND MANAGEMENT OF PERSISTENT PULMONARY HYPERTENSION IN NEWBORNS/YENIDOGANLARDA PERSISTAN PULMONER HIPERTANSIYON TANISI VE YONETIMINDE N-TERMINAL PROHORMON BRAIN NATRIURETIK PEPTID

Objective: This study aimed to investigate the levels and utility of amino/N-terminal prohormone of brain natriuretic peptide (NT-proBNP) in the diagnosis of neonatal persistent pulmonary hypertension (PPHT). Materials and Methods: Infants born at [greater than or equal to] 34 weeks of gestation wer...

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Veröffentlicht in:İstanbul Tıp Fakültesi dergisi = Journal of the Istanbul Faculty of Medicine 2022-06, Vol.85 (2), p.228
Hauptverfasser: Tufekci, Sinan, Kizilca, Ozgur, Aygun, Erhan
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Sprache:eng
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Zusammenfassung:Objective: This study aimed to investigate the levels and utility of amino/N-terminal prohormone of brain natriuretic peptide (NT-proBNP) in the diagnosis of neonatal persistent pulmonary hypertension (PPHT). Materials and Methods: Infants born at [greater than or equal to] 34 weeks of gestation were included in this retrospective cross-sectional study. In total, 33 newborns diagnosed with PPHT were included in the patient group and 50 healthy newborns were included in the control group. Patient and control groups were compared in terms of plasma NT-proBNP levels measured in the umbilical cord (UC) and at 72 hours of life. Results: The NT-proBNP levels in UC and at 72 hours were significantly higher in neonates with PPHT compared to controls (p2760.5 pg/ml, sensitivity was 90.7%, and specificity was 96.6% (p1414 pg/ml, sensitivity was 95.9%, and specificity was 91.2% (p
ISSN:1305-6433
DOI:10.26650/IUITFD.957968