Granulomatous skin infections/Granulomatoz deri enfeksiyonlari

Granulomatous skin disorders are a heterogeneous group of disorders characterized by granuloma formation on histopathology. They may be triggered by various stimuli, including infectious and non-infectious stimuli (foreign bodies, malignancy, metabolites, and chemicals), of different etiological ori...

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Veröffentlicht in:Turkish Archives of Dermatology and Venereology 2021-03, Vol.55 (1), p.1
Hauptverfasser: Rota, Didem Dincer, Emeksiz, Mehmet Can
Format: Artikel
Sprache:eng ; tur
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Zusammenfassung:Granulomatous skin disorders are a heterogeneous group of disorders characterized by granuloma formation on histopathology. They may be triggered by various stimuli, including infectious and non-infectious stimuli (foreign bodies, malignancy, metabolites, and chemicals), of different etiological origins. Although pathophysiological mechanisms are still poorly understood, infectious granuloma formation may occur if the patient's immune system could not eliminate an agent. Clinically, localized or disseminated infectious granuloma formation can be related to the infectious agent's pathogenicity or the patient's immunity. Typical infectious agents causing infectious granulomatous reactions are mycobacteria, fungal infections, or parasites, such as leishmaniasis. This review aims to summarize granulomatous skin diseases encountered more frequently in our clinical experience because of infectious causes. Keywords: Granulomatous, skin, infection Granulomatoz deri hastaliklari histopatolojisinde granulom olusumu ile karakterize heterojen bir hastalik grubudur. Etiyolojik olarak, enfeksiyoz ve enfeksiyoz olmayan da (yabanci cisim, malignite, metabolitler ve kimyasallar) dahil olmak uzere cok cesitli uyaranlarla tetiklenebilirler. Her ne kadar patofizyolojik mekanizmalar hala yeterince anlasilamasa da, hastanin bagisiklik sistemi bir ajani ortadan kaldiramadiginda enfeksiyoz granulom olusumu meydana gelebilir. Klinik olarak lokalize veya dissemine enfeksiyoz granulom olusumu, ajanin patojenitesi veya hastanin bagisikligi ile ilgili olabilir. Enfeksiyoz granulomatoz reaksiyonlara neden olan tipik ajanlar: Mikobakteriler, mantar enfeksiyonlari veya laysmanya gibi parazitlerdir. Bu derlemede, klinik deneyimimizde daha sik karsilasilabilecek enfeksiyoz nedenli granulomatoz deri hastaliklarini ozetlemeyi amacladik. Anahtar Kelimeler: Granulomatoz, deri, enfeksiyon
ISSN:1019-214X
DOI:10.4274/turkderm.galenos.2020.16362