Association of Systemic Inflammation with Depressive Symptoms in Individuals with COPD

Rationale: Depression is a prevalent comorbidity of chronic obstructive pulmonary disease (COPD) that, along with COPD, has been associated with inflammation. An association between inflammation and depression in COPD has not been validated in a large COPD cohort. Methods: Individuals from the Unive...

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Veröffentlicht in:	International journal of chronic obstructive pulmonary disease 2021-01, Vol.16, p.2515-2522
Hauptverfasser:	Strollo, Hilary C., Nouraie, Seyed M., Hoth, Karin F., Riley, Craig M., Karoleski, Chad, Zhang, Yingze, Hanania, Nicola A., Bowler, Russell P., Bon, Jessica, Sciurba, Frank C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Airway management Analysis bdi beck depression inventory Biomarkers Chronic obstructive pulmonary disease Cohort Studies Comorbidity copdgene crp depression Depression - diagnosis Depression - epidemiology Depression, Mental Diabetes Enrollments Female hads Humans il-6 Inflammation Inflammation - diagnosis Inflammation - epidemiology Life Sciences & Biomedicine Lung cancer Lung diseases Lung diseases, Obstructive Male Mental depression Mortality Original Research Pathogenesis Pulmonary Disease, Chronic Obstructive - diagnosis Pulmonary Disease, Chronic Obstructive - epidemiology Questionnaires Respiratory System Risk factors sccor Science & Technology Smoking Spirometry tnf-a Tumor necrosis factor-TNF Variables
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Zusammenfassung:	Rationale: Depression is a prevalent comorbidity of chronic obstructive pulmonary disease (COPD) that, along with COPD, has been associated with inflammation. An association between inflammation and depression in COPD has not been validated in a large COPD cohort. Methods: Individuals from the University of Pittsburgh SCCOR cohort and the COPDGene cohort with tobacco use history and airway obstruction (FEV1/FVC
ISSN:	1178-2005 1176-9106 1178-2005
DOI:	10.2147/COPD.S322144