Lactate kinetics in intensive care unit admissions due to diabetic ketoacidosis

Aims: We conducted this study to investigate the clinical significance of lactate kinetics in patients admitted to the intensive care unit (ICU) for diabetic ketoacidosis (DKA). Methods: This retrospective study was conducted between November 1, 2016, and December 31, 2020. Serial lactate measurements (at the hospital admission, ICU admission, and in 24 hours periods until 48 hours of ICU stay) of the patients admitted to our ICU with a diagnosis of DKA were recorded. Results: Forty patients were included in the study (mean age: 50.6[+ or -]19.4 years, female 60%). Eighty-five percent (n=34) of patients had increased (>2 mmol/L) blood lactate levels on admission. There was no significant difference between the low (lactate