Mersin'de Bir Devlet Hastanesine Basvuran Gebelerde Toxoplasma gondii Seroprevalansi, 2019/Seroprevalence of Toxoplasma gondii in Pregnant Women Admitted to a State Hospital in Mersin, 2019

Amaç: Bu çalismada, rutin gebelik takibi için hastaneye basvuran gebelerdeki Toxoplasma gondii (T. gondii) seroprevalansinin retrospektif olarak ortaya konmasi amaçlanmistir. Yöntemler: Ocak 2019-Aralik 2019 tarihleri arasinda rutin gebelik takibi ile basvuran 16-49 yas arasi gebelerin anti-T. gondii IgM-IgG antikor degerleri retrospektif olarak incelenmistir. Bulgular: Anti-T. gondii IgG testi yapilan 1,832 serum örneginin %28,7'si pozitif, %70,4'ü negatif ve %0,9'u sinir deger olarak sonuç vermistir. Anti-T. gondii IgM içinse 1,844 serum örneginin %0,7'si pozitif, %99,5'i negatif ve %0,1'i ise sinir deger olarak degerlendirilmistir. Anti-Toxoplasma IgM'de yas azaldikça pozitiflik oranlarinda artis oldugu (r=0,144, p=0,001), anti-Toxoplasma IgG'de ise yas artisi ile birlikte pozitiflik oranlarinin arttigi gözlenmistir (r=0,061, p=0,001). Uyruk olarak degerlendirildiginde ise Suriyeli gebe kadinlarda tespit edilen anti-Toxoplasma IgM (p=0,008) ve IgG (p=0,001) pozitiflik oranlarinin Türk gebe kadinlara kiyasla daha yüksek oldugu görülmüstür. Sonuç: Çalismamizda, gebe kadinlarin önemli bir bölümünün etkene karsi bagisikliginin olmadigi gözlenmis ve dolayisi ile bu kisilerin parazitten korunma yöntemleri konusunda bilgilendirilmelerinin olasi bir enfeksiyonu engellemek açisindan önem arz ettigi sonucuna ulasilmistir. Anahtar kelimeler: Toxoplasma gondii, seroprevalans, Mersin Objective: This study aimed to retrospectively reveal the seroprevalence of Toxoplasma gondii (T. gondii) in pregnant women with routine pregnancy follow-up. Methods: Anti-T. gondii IgM-IgG antibody values of pregnant women aged 16-49 years, who had routine pregnancy follow-up in January-December 2019 were analysed retrospectively. Results: Of the 1.832 serum samples, in which the anti-T. gondii IgG test was studied, 28.7% were found to be positive, 70.4% were negative and 0.9% was found to be suspicious. For anti-T. gondii IgM, 0.7% of the 1.844 serum samples were evaluated as positive, 99.5% as negative and 0.1% as suspicious. The positivity rates was observed to increase as age decreases in anti-Toxoplasma IgM (r=0.144, p=0.001), and the positivity rates increase as the age increases in the anti-Toxoplasma IgG (r=0.061, p=0.001). In the nationality evaluation, the anti-T. gondii IgM and IgG positivity rates were observed to be higher in Syrian pregnant women compared to Turkish pregnant women. Conclusion: In our study, a significant portion of pregnant women were observed to be non-i