Spinal Metastasis as Presenting Feature of Follicular Type Thyroid Carcinoma: A Case Report and Review of the Literature/Spinal Metastazla Belirti Veren Follikuler Tip Tiroid Karsinomu: Olgu Sunumu ve Literatur Taramas?
Objective: Follicular type thyroid carcinoma (FTC) rarely presented with spinal metastasis. We aimed to report such a case and to review the literature. Method: A 45 year old male with L2 metastasis of FTC was reported, and other 26 cases were found in literature. Characteristics of the patients and...
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Veröffentlicht in: | Bagcilar Medical Bulletin 2019-03, Vol.4 (1), p.1 |
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Zusammenfassung: | Objective: Follicular type thyroid carcinoma (FTC) rarely presented with spinal metastasis. We aimed to report such a case and to review the literature. Method: A 45 year old male with L2 metastasis of FTC was reported, and other 26 cases were found in literature. Characteristics of the patients and tumors were evaluated. Results: Total 27 patients were 55.2 [+ or -] 15 years of age, and male/ female ratio was 12/15. Nineteen patients had paresis of extremities, 9 of them could not mobilize on admission. Total resection of the spinal tumor had been performed in 14 cases and subtotal resection in 5. Radioactive iodine treatment had been added in 20 cases with or without other adjuvant treatment. Twenty-three patients had been followed for 43.7 [+ or -] 53.2 months. Only four of them died 214, 66, 36 and 7 months after their presentations. Out of other 19 cases, 13 had been neurologically normal. Type of surgery (total resection versus others) the only factor affecting outcome. In the patients treated with total resection, outcome had been statistically better. Conclusion: Spinal metastasis as initial finding is very rare in the patients with FTC. However, prognosis is quite well with total tumor resection and adjuvant treatment. This cancer type must be kept in mind for differential diagnosis and must be screened in the patients with spinal tumors. Keywords: Differentiated thyroid carcinoma, follicular type thyroid carcinoma, spinal metastasis, spinal tumor Amac: Follikuler tip tiroid karsinomu (FTK) nadiren spinal metastazla belirti verir. Boyle bir olgu sunmayi ve bu konuda literatur taramayi amacladik. Yontem: Lomber 2 spinal metastazla belirti veren 45 yasinda erkek FTK olgusu sunuldu ve literaturde benzer 26 olgu bulundu. Tum olgularin ozellikleri degerlendirildi. Bulgular: Toplam 27 olgu 55,2 [+ or -] 15 yasindaydi (35-88 arasinda, ortalama [+ or -] SS) ve erkek/kadin orani 12/15 idi. Basvuruda 19 olguda kol ve/veya bacaklarda gucsuzluk vardi ve 9'u mobilize olamiyordu. Spinal tumor 14 olguda total, 5 olguda subtotal cikarildi. Yirmi olguya radyoaktif iyot tedavisi eklendi. Olgularin 23'u 3-214 ay (43,7 [+ or -] 53,2, ortalama [+ or -] SS) sureyle izlenmisti, sadece 4 olgu basvurudan 214, 66, 36 ve 7 ay sonra olmustu. Halen sag olan 19 olgunun 13'u norolojik olarak normaldi. Uygulanan cerrahi tipi (total cikarmaya karsilik diger cerrahi tipleri) son durumu etkileyen tek faktor olarak saptandi. Tumoru total cikarilan hastalarda sondurum anlamli olarak |
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ISSN: | 2547-9431 2547-9431 |
DOI: | 10.4274/BMB.galenos.2019.26888 |