Clinical analysis and RNA findings in a family with SARS‑CoV‑2 infection: Case reports

The present study reported the epidemiological, clinical features, laboratory data and management of a family of 5 members with COVID-19. It was found that the initial clinical manifestations of the 3 adults were fever, cough and sore throat; they all exhibited a higher erythrocyte sedimentation rate (ESR) and higher serum glucose level. The 2 children only exhibited a mild dry cough. As regards the 2-month-old infant who was breast-fed, the possible infection source was close contact with family members or respiratory droplets. Her mother's breast milk was negative for SARS-CoV-2, as shown by RT-PCR. The two children persisted to be positive for SARS-CoV-2 by anal swab after being released from the hospital, although they were negative for SARS-CoV-2 by a throat swab. Key words: severe acute respiratory syndrome coronavirus 2, COVID-19, family cluster, RNA