p63.sup.+Krt5.sup.+ distal airway stem cells are essential for lung regeneration

p63.sup.+Krt5.sup.+ distal airway stem cells are essential for lung regeneration

Many patients experiencing sudden loss of lung tissue somehow undergo full recovery; here this recovery is traced to a discrete population of lung stem cells that are not only essential for lung regeneration but can be cloned and then transplanted to other mice to contribute new lung tissue.

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Veröffentlicht in:Nature (London) 2015-01, Vol.517 (7536), p.616
Hauptverfasser: Zuo, Wei, Zhang, Ting, Wu, Daniel Zheng'An, Guan, Shou Ping, Liew, Audrey-Ann, Yamamoto, Yusuke, Wang, Xia
Format: Artikel
Sprache:eng
Schlagworte:
Health aspects
Influenza
Influenza viruses
Lung diseases
Resveratrol
Stem cells
Transplantation
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Zusammenfassung:Many patients experiencing sudden loss of lung tissue somehow undergo full recovery; here this recovery is traced to a discrete population of lung stem cells that are not only essential for lung regeneration but can be cloned and then transplanted to other mice to contribute new lung tissue.
ISSN:0028-0836
DOI:10.1038/nature13903