Evaluation and prognostic value of Cv-aC[O.sub.2]/Da-v[O.sub.2] in patients with septic shock receiving fluid resuscitation Cv-aC[O.sub.2]/Ca-v[O.sub.2]

The present study aimed to evaluate the prognostic value of venous-arterial C[O.sub.2] to arterial-venous [O.sub.2] (Cv-aC[O.sub.2]/Da-v[O.sub.2]) for patients with septic shock treated by fluid resuscitation. A total of 108 cases who received fluid resuscitation for septic shock at the Intensive Care Unit were retrospectively screened according to the 2012 surviving sepsis campaign guidelines. Patients were divided into 2 groups according to the Cv-aC[O.sub.2]/Da-v[O.sub.2] ratio at 6 h after fluid resuscitation: Group A, Cv-aC[O.sub.2]/Da-v[O.sub.2] >1; group B, Cv-aC[O.sub.2]/Da-v[O.sub.2] [less than or equal to] 1. The resuscitation target rate and transfused resuscitation volume at 6 h exhibited no significant difference between the 2 groups. The cardiac output at 6 and 24 h, as well as the ratio of patients who reached the target of resuscitation within 24 h, the 24-h lactic acid clearance rate and the number of cases with central venous oxygen saturation >70% were significantly decreased in group A compared with those in group B (all P