Correction: Upregulated claudin-1 expression promotes colitis-associated cancer by promoting [beta]-catenin phosphorylation and activation in Notch/p-AKT-dependent manner

In Fig. 1 legend, should read as follows: Cld-1 intensifies colitis, leads to impaired recovery from DSS induction and triggers dysplasia: a Schematic illustration of the experimental protocol. Age-matched and sex-matched WT (n = 8) and Cld-1 Tg (n = 8) mice were treated with 2.5% DSS in drinking wa...

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Veröffentlicht in:Oncogene 2019-09, Vol.38 (38), p.6566
Hauptverfasser: Gowrikumar, Saiprasad, Ahmad, Rizwan, Uppada, Srijayaprakash Babu, Washington, Mary K, Shi, Chanjuan, Singh, Amar B, Dhawan, Punita
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Sprache:eng
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Zusammenfassung:In Fig. 1 legend, should read as follows: Cld-1 intensifies colitis, leads to impaired recovery from DSS induction and triggers dysplasia: a Schematic illustration of the experimental protocol. Age-matched and sex-matched WT (n = 8) and Cld-1 Tg (n = 8) mice were treated with 2.5% DSS in drinking water for 7 days ad libitum (colitis group), followed by drinking water for 10 days (DSS recovery group). b Representative histological images of WT and Cld-1 Tg mice under DSS and DSS recovery protocol showing regenerative crypts in WT DSS Recovery and dysplastic crypts in Cld-1 Tg Recovery. c The mean changes in body weight of the WT and Cld-1 Tg mice after being fed with 2.5% DSS were measured every day until day 7 for the colitis group and day 10 for the DSS recovery group. The percentage of mice possessing dysplastic crypt in the recovery protocol among WT and Cld-1 Tg groups. Results are statistically significant at p < 0.05. Values sharing following symbols differ significantly, asterisk (*) compared with WT DSS Recovery.
ISSN:0950-9232
DOI:10.1038/s41388-019-0864-9