Antimicrobial Effectiveness of Bioactive Phenazine Against Clinical Isolates
The bioactive phenazine extracted from Pseudomonas aeruginosa were obtained from the clinical isolates collected from different pathological laboratories of Karachi, Pakistan and its antimicrobial activity was assayed against pathogenic microorganisms. It was found that various gram negative and gra...
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Veröffentlicht in: | Pakistan journal of scientific and industrial research. Series B: biological sciences 2019-03, Vol.62 (1), p.58-60 |
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container_title | Pakistan journal of scientific and industrial research. Series B: biological sciences |
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creator | Saeed, Fasiha Ahmed, Fariha Afaque, Farkhanda Mehmood, Kholud Nadeem, Syeda Ghufrana |
description | The bioactive phenazine extracted from Pseudomonas aeruginosa were obtained from the clinical isolates collected from different pathological laboratories of Karachi, Pakistan and its antimicrobial activity was assayed against pathogenic microorganisms. It was found that various gram negative and gram positive bacteria and some species of Candida shown to be sensitive against pyocyanin. Extraction was carried out by using chloroform and agar well diffusion protocol was performed for its antimicrobial effectiveness. The maximum average zone of inhibition observed by 20 p.L of purified pyocyanin was 16 mm that was against Proteus sp. in case of bacteria and 17 mm against Candida sp. Keywords: phenazine, Pseudomonas aeruginosa, antimicrobial activity, pyocyanin |
doi_str_mv | 10.52763/PJSIR.BIOL.SCI.62.1.2019.58.60 |
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Series B: biological sciences</title><description>The bioactive phenazine extracted from Pseudomonas aeruginosa were obtained from the clinical isolates collected from different pathological laboratories of Karachi, Pakistan and its antimicrobial activity was assayed against pathogenic microorganisms. It was found that various gram negative and gram positive bacteria and some species of Candida shown to be sensitive against pyocyanin. Extraction was carried out by using chloroform and agar well diffusion protocol was performed for its antimicrobial effectiveness. The maximum average zone of inhibition observed by 20 p.L of purified pyocyanin was 16 mm that was against Proteus sp. in case of bacteria and 17 mm against Candida sp. 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It was found that various gram negative and gram positive bacteria and some species of Candida shown to be sensitive against pyocyanin. Extraction was carried out by using chloroform and agar well diffusion protocol was performed for its antimicrobial effectiveness. The maximum average zone of inhibition observed by 20 p.L of purified pyocyanin was 16 mm that was against Proteus sp. in case of bacteria and 17 mm against Candida sp. Keywords: phenazine, Pseudomonas aeruginosa, antimicrobial activity, pyocyanin</abstract><pub>Pakistan Council of Scientific and Industrial Research</pub><doi>10.52763/PJSIR.BIOL.SCI.62.1.2019.58.60</doi><tpages>3</tpages></addata></record> |
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source | Alma/SFX Local Collection |
subjects | Bacteria Microorganisms Pathogenic microorganisms Pseudomonas aeruginosa |
title | Antimicrobial Effectiveness of Bioactive Phenazine Against Clinical Isolates |
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