Antimicrobial Effectiveness of Bioactive Phenazine Against Clinical Isolates

The bioactive phenazine extracted from Pseudomonas aeruginosa were obtained from the clinical isolates collected from different pathological laboratories of Karachi, Pakistan and its antimicrobial activity was assayed against pathogenic microorganisms. It was found that various gram negative and gra...

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Veröffentlicht in:Pakistan journal of scientific and industrial research. Series B: biological sciences 2019-03, Vol.62 (1), p.58-60
Hauptverfasser: Saeed, Fasiha, Ahmed, Fariha, Afaque, Farkhanda, Mehmood, Kholud, Nadeem, Syeda Ghufrana
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container_title Pakistan journal of scientific and industrial research. Series B: biological sciences
container_volume 62
creator Saeed, Fasiha
Ahmed, Fariha
Afaque, Farkhanda
Mehmood, Kholud
Nadeem, Syeda Ghufrana
description The bioactive phenazine extracted from Pseudomonas aeruginosa were obtained from the clinical isolates collected from different pathological laboratories of Karachi, Pakistan and its antimicrobial activity was assayed against pathogenic microorganisms. It was found that various gram negative and gram positive bacteria and some species of Candida shown to be sensitive against pyocyanin. Extraction was carried out by using chloroform and agar well diffusion protocol was performed for its antimicrobial effectiveness. The maximum average zone of inhibition observed by 20 p.L of purified pyocyanin was 16 mm that was against Proteus sp. in case of bacteria and 17 mm against Candida sp. Keywords: phenazine, Pseudomonas aeruginosa, antimicrobial activity, pyocyanin
doi_str_mv 10.52763/PJSIR.BIOL.SCI.62.1.2019.58.60
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2223-2567
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subjects Bacteria
Microorganisms
Pathogenic microorganisms
Pseudomonas aeruginosa
title Antimicrobial Effectiveness of Bioactive Phenazine Against Clinical Isolates
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