Depression and anxiety disorder in hyperemesis gravidarum: A prospective case-control study/ Hiperemezis gravidarumlu kadinlarda depresyon ve anksiyete bozuklugu: Prospektif olgu kontrol calismasi

Objective: To assess the anxiety and depression status of women with hyperemesis gravidarum (HG); the risk factors for developing both depression and anxiety in women with HG were evaluated. Materials and Methods: A total of 200 women, 100 diagnosed as having HG before the 20th week of gestation at a tertiary referral center and 100 gestational-age-matched controls were enrolled. The socio-demographic data and the depression and anxiety scores, as assessed using the Beck depression and anxiety inventory were compared between the two groups. Results: The median depression and anxiety scores were significantly higher in the HG group compared with controls (19.5 vs. 9.0 and 22.0 vs. 10.0). Women with HG have the highest relative risks for moderate depression and severe anxiety [relative risk (RR): 16.88 and RR: 20.50, respectively]. In the univariate analysis, having HG, low education level, low income and poor social relationships were significant predictors of depression and having HG. Moreover, poor social relationships significantly predicted the presence of anxiety disorder. However, having HG and poor social relationships were found as the only independent predictors of both depression and anxiety Patients with HG were 5.5 and 6.7 times more prone to having depression and anxiety disorder compared with controls, respectively Conclusion: Both depression and anxiety disorder were more frequent in women with HG who have weak family and social relationships, lower education and income levels. Therefore, the determination of the psychological status of women with HG should be an integral part of the evaluation. Keywords: Hyperemesis gravidarum, pregnancy, depression, anxiety disorder Oz Amac: Arastirmanin birincil amaci, hiperemezis gravidarum (HG) olan kadinlarin anksiyete ve depresyon durumlarini degerlendirmektir. Ayrica, tum gruptaki depresyon ve anksiyete icin risk faktorlerini de degerlendirdik. Gerec ve Yontemler: Gebeligin 20. haftasindan once ucuncu basamak bir merkezde HG teshisi konan 100 kadin ve gebelik haftasi eslestirilen 100 kontrol olmak uzere toplam 200 kadin calismaya dahil edildi. Sosyo-demografk veriler ve Beck depresyon ve anksiyete envanteri ile degerlendirilen depresyon ve anksiyete skorlari iki grup arasinda karsilastirildi. Bulgular: Medyan depresyon ve anksiyete skorlari HG grubunda kontrol grubuna gore anlamli derecede yuksekti (sirasiyla 19,5 ve 9,0 ve 22,0 ve 10,0). Orta sinif depresyon ve siddetli kaygi acisindan HGli kadinlar